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Molecular Reality Corporation is an American company that builds instruments for counting and identifying particles and molecules one at a time, as they pass through a hole in a membrane. Kent Kemmish and Charles Gaillard founded it in 2018 as demonpore, inc., a name taken from Maxwell's demon, the imaginary being who sorts molecules at a door; it took its present name in 2021, and its founder later explained the change: "you can't name a biotech startup after Maxwell's Demon in the age of Qanon." Its central idea is the juxtapore, a pore formed where the holes in two sliding membranes overlap, so that the opening can be widened, narrowed or shut while the instrument runs. From a single bench in Arizona the company streams the electric current through a pore to anyone watching online. It runs its research as a role-playing game, Epic Quest Bio, whose players earn experience points for quests, and its guide for visitors is narrated by Keltar, a one-eyed felt puppet who calls himself "a puppet with a processor". In October 2026 it published the design of its own desktop reader, the MR1 Nanopore Reader, under a status line that reads "Designed. Simulated. Built and measured: not yet." (Full article...)
Did you know ...
- ... that the telephone line of Molecular Reality Corporation is answered, in synthesized speech, by a version of Keltar (pictured), a felt puppet who describes himself as "only mostly real"?
- ... that a player who answers every question wrongly still defeats Irrationalis, Dragon of Excessive Pessimism?
- ... that TAB-42, the inspector in the browser game Silver Orange, has "been doing this job for 34 years" and is instructed never to acknowledge "that anything about your job or this situation is unusual"?
- ... that in Maxine's Quest, the scoreboard labeled "Kent" gains 100 points each time Maxine is hurt?
- ... that members of the Molecular Streaming Corps were offered 500 experience points for a tweet that "Doesn't have to go viral, just has to be a banger!", and 50,000 for one that "Doesn't have to be a banger, just has to go viral"?
- ... that a Player Scientist is defined as anyone who "buys an MR series device and enrolls in the game", and that in May 2026 the company was "not ready to ship" the devices?
- ... that the timeline of Molecular Reality Corporation includes a planned game that was renamed because "we didn't ship in 2021"?
- ... that the best afternoon of data in the early history of Molecular Reality Corporation was recorded while its founder was "somewhere else"?
In the news
- Molecupedia replaces the front page of the websites of Molecular Reality Corporation, which since August had shown a single sentence about a brain and an eye. It answers a 500 XP quest, since switched off, for "an awesome (and accurate) wikipedia page".
- A commit renames the company's open instrument design, until then called "Daemon Pore" and "Sentinel", to MR1. It is the second device the company has called MR1.
- Version 1.0.0 of the MR1 Nanopore Reader (render pictured) is released under the GNU Affero General Public License and, five days later, placed in the public domain under CC0, with the status line "Designed. Simulated. Built and measured: not yet."
On this day
February 2
- 2021: United States Patent 10,908,144, on sliding occlusion, is granted, with Kent Kemmish as its inventor.
- 2025: The same patent lapses for non-payment of its maintenance fee.
February 4
- 1927: Rolf Landauer, who showed that erasing one bit of information must release a minimum amount of heat (Landauer's principle), is born in Stuttgart.
February 5
- 1914: Alan Hodgkin, who with Andrew Huxley explained the nerve impulse as a flow of sodium and potassium ions across the membrane of the cell (Hodgkin-Huxley model), is born in Banbury.
February 11
- 1898: Leo Szilard, who in 1929 tied the measurements of Maxwell's demon to a cost in entropy, is born in Budapest.
February 15
- 1988: Richard Feynman, who described a future of machines built atom by atom in "There's Plenty of Room at the Bottom", dies in Los Angeles.
February 17
- 1913: Wallace H. Coulter, inventor of the Coulter counter, is born in Little Rock, Arkansas.
February 18
- 1838: Ernst Mach, a physicist who doubted that atoms were real, is born in Moravia.
February 19
- 1916: Ernst Mach dies near Munich.
- 2019: A video on the company's channel records "fields of dna molecules at 100x".
February 20
- 1844: Ludwig Boltzmann, who explained heat and entropy as the statistics of molecules, is born in Vienna.
February 23
- 2026: Maxine receives written instructions describing her as "the friendly, highly energetic, fast-talking cartoon representation of a Maxwell's Demon".
March 17
- 2026: Kent Kemmish records the first of 83 recordings of Radio KENT.
March 20
- 1944: Erwin Neher, who with Bert Sakmann recorded the current through a single ion channel (Erwin Neher and Bert Sakmann), is born in Landsberg am Lech.
March 28
- 2026: EQBio-OS, the company's members' software, opens with the message "You're looking at the operating system of a real-life biotech startup, Molecular Reality Corporation."
March 29
- 2025: The domain epicquest.bio is registered.
- 2026: Kemmishtree posts "rain of blood", "Focused Ion Beam pore" and "Flossing with DNA" to the members' inbox, among more than twenty messages in two days.
April 10
- 2026: The company's calendar holds a "LATE NIGHT SAVE THE WORLD EMERGENCY BROADCAST".
April 14
- 2003: The Human Genome Project announces that it has finished sequencing the human genome.
April 17
- 1942: Jean Perrin, whose experiments on Brownian motion persuaded physicists that molecules exist, dies in New York.
April 25
- 1953: Nature publishes the double-helix model of DNA.
- 2026: The company's calendar holds a "Saturday TELETHON". A message dated the same day thanks members "for attending our sparsely attended meeting".
May 2
- 2026: The company's calendar holds a "May Day All Hands Meeting".
May 7
- 2026: An EDR4 amplifier and a flow cell in Arizona are connected for the company's first end-to-end live streaming test. A commit the same day reads "Remember to add all the maxine files."
May 9
- 2017: Priority date of Kent Kemmish's patent application "Stacks of coaligned nanopores and fabrication and uses thereof".
- 2018: The application is filed, one year to the day later.
May 11
- 1905: Annalen der Physik receives Albert Einstein's paper on the motion of small particles suspended in a liquid, whose predictions Jean Perrin tested from 1908 to establish the reality of molecules.
- 1918: Richard Feynman is born in New York City.
May 18
- 2026: The company's calendar holds an "Epic Jamboree!"
June 12
- 1942: Bert Sakmann is born in Stuttgart.
June 13
- 1831: James Clerk Maxwell is born in Edinburgh.
- 2026: The live molecular stream becomes the front page of the company's site, and the members' software moves to an address of its own.
June 26
- 1824: William Thomson, who in 1874 named Maxwell's sorting being a demon, is born in Belfast.
- 2000: A working draft of the human genome is announced at the White House (Human Genome Project).
July 18
- 2021: The domain molecularreality.com is registered.
July 22
- 2026: The company builds Silver Orange, a "surreal 80s-arcade browser game" with no molecular content.
July 24
- 2026: Over seven hours and 26 minutes, the company renders "IRIDIAN: 197 Views of the Seeing Eye", a gallery of animated eyes. Eighteen of the 197 fail to render.
August 7
- 1998: Wallace H. Coulter dies in Miami.
August 9
- 1776: Amedeo Avogadro, after whom the number of molecules in a mole is named (Avogadro constant), is born in Turin.
August 18
- 2026: An "ultraminimalist splash with email-code contact form" becomes the front page of the company's site.
August 19
- 2026: The front page is rebuilt around one sentence: "everybody's racing to build the brain, we're building the eye."
August 23
- 2024: The domain keltar.ai is registered.
August 26
- 1723: Antonie van Leeuwenhoek, who saw bacteria through microscopes of his own making, dies in Delft.
August 27
- 1949: Wallace H. Coulter files his patent application on "Means for counting particles suspended in a fluid", the instrument later sold as the Coulter counter.
September 5
- 1906: Ludwig Boltzmann dies at Duino, near Trieste.
September 9
- 1737: Luigi Galvani, whose experiments on the legs of frogs led him to propose animal electricity, is born in Bologna.
September 26
- 2026: The company builds the data for The Hole World, its atlas of molecular sensing: 2,112 entries, from 1,596 academic groups to 15 instrument makers.
September 30
- 1870: Jean Perrin is born in Lille.
October 3
- 1956: Wallace H. Coulter presents the Model A, the first commercial Coulter counter, in Chicago. It counts red blood cells at about 3,300 a second.
October 15
- 2026: A commit to the MR1 repository "Adds AGPLv3 license to all relevant source files and root directory".
October 16
- 1948: Wallace H. Coulter's dated notes record the first demonstration of the Coulter principle.
- 2026: Version 1.0.0 of the MR1 Nanopore Reader design is released under the GNU Affero General Public License.
October 18
- 2026: A commit renames "Daemon Pore" and "Sentinel" to MR1 throughout the company's instrument repository.
October 20
- 1953: Wallace H. Coulter is granted US Patent 2,656,508, the basis of the Coulter counter.
October 21
- 2026: A commit to the MR1 repository places the whole project in the public domain under CC0 1.0, five days after its first release under the GNU Affero General Public License.
October 24
- 1632: Antonie van Leeuwenhoek is born in Delft.
October 25
- 2026: Molecupedia becomes the front page of the websites of Molecular Reality Corporation.
November 5
- 1879: James Clerk Maxwell dies in Cambridge.
November 11
- 2025: The repository that later becomes the MR1 Nanopore Reader receives its first commit, titled "first commit".
November 15
- 2018: The patent application on sliding occlusion is published as US 2018/0328909.
November 22
- 1917: Andrew Huxley is born in Hampstead, London.
November 26
- 1996: The Proceedings of the National Academy of Sciences reports single strands of DNA and RNA detected one at a time as they pass through a protein pore, alpha-hemolysin, the experiment from which nanopore sequencing grew.
December 4
- 1798: Luigi Galvani dies in Bologna.
December 7
- 2025: The company posts a video invitation to the Church of Sequence Space.
December 11
- 1867: James Clerk Maxwell describes, in a letter to Peter Guthrie Tait, the sorting being later named Maxwell's demon.
- 1926: Jean Perrin gives his Nobel lecture, "Discontinuous Structure of Matter".
December 20
- 1998: Alan Hodgkin dies in Cambridge.
December 23
- 2025: A commit reads "Add Sentinel Nanopore Reader Rev 11 SCAD file". Sentinel was an early name of the MR1 Nanopore Reader.
December 24
- 2014: The domain demonpore.com is registered, on Christmas Eve.
December 29
- 1959: Richard Feynman gives the talk "There's Plenty of Room at the Bottom" at a meeting of the American Physical Society at Caltech.
The records of Molecular Reality Corporation date the following events by year alone, so any of them may have happened on this date:
- 2012: Kent Kemmish first thinks of mechanical nanopores, pores whose opening can be changed by moving solid parts.
- 2013: In the company's fiction, Kemmishtree and Keltar found the Church of Sequence Space.
- 2021: demonpore, inc. becomes Molecular Reality Corporation.
- 2022: Kemmish writes "Our North Star: Utility-Scale Molecular Sensing", the best he "could do one night in 2022".
- 2024: The volunteer community later called the Molecular Streaming Corps is founded as the Molecular Streaming Services Corps.
Today's featured picture
![]() | An EDR4, a USB patch-clamp amplifier made by Elements srl, seated in a 3D-printed cradle above a white flow cell with red wing nuts on the bench of Molecular Reality Corporation. The company's guide calls it "the laboratory's ear". It samples the current through the pore two hundred thousand times a second, and the unit that does the company's streaming carries the serial number "e4 00044". (EDR4) Photograph: Molecular Reality Corporation |
Other areas of Molecupedia
- About Molecupedia: who writes this encyclopedia, why its company facts carry sources, and how to reach the company.
- Help desk: how to read Molecupedia. Help with editing it is not offered, because it cannot be edited.
- Village pump: there is none. Discussion takes place on the talk pages, among editors whose usernames are invented, as on Talk:Molecular Reality Corporation.
- Reference desk: questions about the company's science may be put to Keltar on the company's voice line, which a version of him answers in character.
- Content portals: Portal:Molecular Reality and Portal:Nanopores.
- Policies: Neutral point of view, Conflict of interest and the General disclaimer.
Molecupedia's sister projects
Molecupedia is written and hosted by Molecular Reality Corporation, which also hosts a range of other projects that do not exist.
- Molecule Commons
Free media repository - Moleculary
Dictionary and thesaurus - Moleculequote
Collection of quotations - Moleculedata
Free knowledge base
Molecupedia languages
This Molecupedia is written in English. Some of its sources are not: one post in the company's inbox, from the persona Molecular de Unamuno, is in Spanish; another, from the persona Jeanne d'Arc, takes Voltaire's French motto "Ecrasez l'infame!" as its title; and the name of the dragon Irrationalis is Late Latin for "without reason".




